Improving T Cell Receptor On-Target Specificity via Structure-Guided Design

T cell receptors (TCRs) have emerged as a new class of immunological therapeutics. However, though antigen specificity is a hallmark of adaptive immunity, TCRs themselves do not possess the high specificity of monoclonal antibodies. Although a necessary function of T cell biology, the resulting cros...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Hellman, Lance M., Foley, Kendra C., Singh, Nishant K., Alonso, Jesus A., Riley, Timothy P., Devlin, Jason R., Ayres, Cory M., Keller, Grant L.J., Zhang, Yuting, Vander Kooi, Craig W., Nishimura, Michael I., Baker, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369632/
https://ncbi.nlm.nih.gov/pubmed/30617019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.12.010
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados