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Dynamic allostery controls the peptide sensitivity of the Ly49C natural killer receptor

Using a variety of activating and inhibitory receptors, natural killer (NK) cells protect against disease by eliminating cells that have downregulated class I major histocompatibility complex (MHC) proteins, such as in response to cell transformation or viral infection. The inhibitory murine NK rece...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ma, Jiaqi, Ayres, Cory M., Hellman, Lance M., Devlin, Jason R., Baker, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138769/
https://ncbi.nlm.nih.gov/pubmed/33891944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100686
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