טוען...
Structural dissimilarity from self drives neoepitope escape from immune tolerance
T cell recognition of peptides incorporating non-synonymous mutations, or neoepitopes, is a cornerstone of tumor immunity and forms the basis of new immunotherapy approaches including personalized cancer vaccines. Yet as they are derived from self-peptides, the means through which immunogenic neoepi...
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| הוצא לאור ב: | Nat Chem Biol |
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| Main Authors: | , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8210748/ https://ncbi.nlm.nih.gov/pubmed/32807968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-0610-1 |
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