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Structural dissimilarity from self drives neoepitope escape from immune tolerance
T cell recognition of peptides incorporating non-synonymous mutations, or neoepitopes, is a cornerstone of tumor immunity and forms the basis of new immunotherapy approaches including personalized cancer vaccines. Yet as they are derived from self-peptides, the means through which immunogenic neoepi...
Gorde:
| Argitaratua izan da: | Nat Chem Biol |
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| Egile Nagusiak: | , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8210748/ https://ncbi.nlm.nih.gov/pubmed/32807968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-0610-1 |
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