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High-resolution structure of a Y27W mutant of the Dishevelled2 DIX domain
Dishevelled (Dvl) is a positive regulator of the canonical Wnt pathway that downregulates the phosphorylation of β-catenin and its subsequent degradation. Dvl contains an N-terminal DIX domain, which is involved in its homooligomerization and interactions with regulators of the Wnt pathway. The crys...
Gorde:
| Argitaratua izan da: | Acta Crystallogr F Struct Biol Commun |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
International Union of Crystallography
2019
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6360446/ https://ncbi.nlm.nih.gov/pubmed/30713163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X18018290 |
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