Hypothalamic POMC or MC4R deficiency impairs counterregulatory responses to hypoglycemia in mice

OBJECTIVE: Life-threatening hypoglycemia is a major limiting factor in the management of diabetes. While it is known that counterregulatory responses to hypoglycemia are impaired in diabetes, molecular mechanisms underlying the reduced responses remain unclear. Given the established roles of the hyp...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Metab
Egile Nagusiak: Tooke, Benjamin P., Yu, Hui, Adams, Jessica M., Jones, Graham L., Sutton-Kennedy, Talisha, Mundada, Lakshmi, Qi, Nathan R., Low, Malcolm J., Chhabra, Kavaljit H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2018
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358536/
https://ncbi.nlm.nih.gov/pubmed/30503832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.11.004
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