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Hypothalamic POMC deficiency increases circulating adiponectin despite obesity

OBJECTIVE: The steep rise in the prevalence of obesity and its related metabolic syndrome have become a major worldwide health concerns. Melanocortin peptides from hypothalamic arcuate nucleus (Arc) POMC neurons induce satiety to limit food intake. Consequently, Arc Pomc-deficient mice (ArcPomc(−/−)...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Yu, Hui, Chhabra, Kavaljit H., Thompson, Zoe, Jones, Graham L., Kiran, Sylee, Shangguan, Gary, Low, Malcolm J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7082555/
https://ncbi.nlm.nih.gov/pubmed/32244188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.01.021
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