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Disease‐associated tau impairs mitophagy by inhibiting Parkin translocation to mitochondria
Accumulation of the protein tau characterises Alzheimer's disease and other tauopathies, including familial forms of frontotemporal dementia (FTD) that carry pathogenic tau mutations. Another hallmark feature of these diseases is the accumulation of dysfunctional mitochondria. Although disease‐...
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| Pubblicato in: | EMBO J |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6356067/ https://ncbi.nlm.nih.gov/pubmed/30538104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899360 |
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