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Disease‐associated tau impairs mitophagy by inhibiting Parkin translocation to mitochondria
Accumulation of the protein tau characterises Alzheimer's disease and other tauopathies, including familial forms of frontotemporal dementia (FTD) that carry pathogenic tau mutations. Another hallmark feature of these diseases is the accumulation of dysfunctional mitochondria. Although disease‐...
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| Veröffentlicht in: | EMBO J |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6356067/ https://ncbi.nlm.nih.gov/pubmed/30538104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899360 |
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