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Disease‐associated tau impairs mitophagy by inhibiting Parkin translocation to mitochondria
Accumulation of the protein tau characterises Alzheimer's disease and other tauopathies, including familial forms of frontotemporal dementia (FTD) that carry pathogenic tau mutations. Another hallmark feature of these diseases is the accumulation of dysfunctional mitochondria. Although disease‐...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6356067/ https://ncbi.nlm.nih.gov/pubmed/30538104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899360 |
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