Superoxide drives progression of Parkin/PINK1-dependent mitophagy following translocation of Parkin to mitochondria

Reactive oxygen species (ROS) and mitophagy are profoundly implicated in the pathogenesis of neurodegenerative diseases, such as Parkinson’s disease (PD). Several studies have suggested that ROS are not involved in mitochondrial translocation of Parkin which primes mitochondria for autophagic elimin...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Xiao, Bin, Deng, Xiao, Lim, Grace G Y, Xie, Shaoping, Zhou, Zhi Dong, Lim, Kah-Leong, Tan, Eng-King
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680585/
https://ncbi.nlm.nih.gov/pubmed/29022898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.463
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker