PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1) and PARK2/Parkin mutations cause autosomal recessive forms of Parkinson's disease. Upon a loss of mitochondrial membrane potential (ΔΨ(m)) in human cells, cytosolic Parkin has been reported to be recruited to mitochondria,...

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Detalhes bibliográficos
Main Authors: Vives-Bauza, Cristofol, Zhou, Chun, Huang, Yong, Cui, Mei, de Vries, Rosa L.A., Kim, Jiho, May, Jessica, Tocilescu, Maja Aleksandra, Liu, Wencheng, Ko, Han Seok, Magrané, Jordi, Moore, Darren J., Dawson, Valina L., Grailhe, Regis, Dawson, Ted M., Li, Chenjian, Tieu, Kim, Przedborski, Serge
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806779/
https://ncbi.nlm.nih.gov/pubmed/19966284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911187107
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