SQSTM1/p62 promotes mitochondrial ubiquitination independently of PINK1 and PRKN/parkin in mitophagy

The ubiquitination of mitochondrial proteins labels damaged mitochondria for degradation through mitophagy. We recently developed an in vivo system in which mitophagy is slowed by inhibiting mitochondrial division through knockout of Dnm1l/Drp1, a dynamin related GTPase that mediates mitochondrial d...

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Bibliographic Details
Published in:Autophagy
Main Authors: Yamada, Tatsuya, Dawson, Ted M., Yanagawa, Toru, Iijima, Miho, Sesaki, Hiromi
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844492/
https://ncbi.nlm.nih.gov/pubmed/31339428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1643185
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