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Preconditioning Involves Selective Mitophagy Mediated by Parkin and p62/SQSTM1

Autophagy-dependent mitochondrial turnover in response to cellular stress is necessary for maintaining cellular homeostasis. However, the mechanisms that govern the selective targeting of damaged mitochondria are poorly understood. Parkin, an E3 ubiquitin ligase, has been shown to be essential for t...

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Bibliografiset tiedot
Päätekijät: Huang, Chengqun, Andres, Allen M., Ratliff, Eric P., Hernandez, Genaro, Lee, Pamela, Gottlieb, Roberta A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110820/
https://ncbi.nlm.nih.gov/pubmed/21687634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020975
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