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Parkin-mediated mitophagy is downregulated in browning of white adipose tissue
OBJECTIVE: Browning of white adipose tissue (WAT) promotes increased energy expenditure through the action of uncoupling protein 1 (UCP1), and is an attractive target to promote weight loss in obesity. Lowering of mitochondrial membrane potential by UCP1 is uniquely beneficial in this context; in ot...
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| Gepubliceerd in: | Obesity (Silver Spring) |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5373982/ https://ncbi.nlm.nih.gov/pubmed/28240819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.21786 |
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