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Parkin and PINK1: Much More than Mitophagy

Parkinson’s disease (PD) is a progressive neurodegenerative disease that causes a debilitating movement disorder. While most cases of PD appear to be sporadic, rare Mendelian forms have provided tremendous insight into disease pathogenesis. Accumulating evidence suggests that impaired mitochondria u...

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Detalhes bibliográficos
Main Authors: Scarffe, Leslie A., Stevens, Daniel A., Dawson, Valina L., Dawson, Ted M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075431/
https://ncbi.nlm.nih.gov/pubmed/24735649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2014.03.004
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