Miro proteins prime mitochondria for Parkin translocation and mitophagy

The Parkinson's disease‐associated protein kinase PINK1 and ubiquitin ligase Parkin coordinate the ubiquitination of mitochondrial proteins, which marks mitochondria for degradation. Miro1, an atypical GTPase involved in mitochondrial trafficking, is one of the substrates tagged by Parkin after...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Safiulina, Dzhamilja, Kuum, Malle, Choubey, Vinay, Gogichaishvili, Nana, Liiv, Joanna, Hickey, Miriam A, Cagalinec, Michal, Mandel, Merle, Zeb, Akbar, Liiv, Mailis, Kaasik, Allen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2018
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331716/
https://ncbi.nlm.nih.gov/pubmed/30504269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899384
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