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Miro proteins prime mitochondria for Parkin translocation and mitophagy
The Parkinson's disease‐associated protein kinase PINK1 and ubiquitin ligase Parkin coordinate the ubiquitination of mitochondrial proteins, which marks mitochondria for degradation. Miro1, an atypical GTPase involved in mitochondrial trafficking, is one of the substrates tagged by Parkin after...
Tallennettuna:
| Julkaisussa: | EMBO J |
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| Päätekijät: | , , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
John Wiley and Sons Inc.
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6331716/ https://ncbi.nlm.nih.gov/pubmed/30504269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899384 |
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