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Miro proteins prime mitochondria for Parkin translocation and mitophagy
The Parkinson's disease‐associated protein kinase PINK1 and ubiquitin ligase Parkin coordinate the ubiquitination of mitochondrial proteins, which marks mitochondria for degradation. Miro1, an atypical GTPase involved in mitochondrial trafficking, is one of the substrates tagged by Parkin after...
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| 發表在: | EMBO J |
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| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley and Sons Inc.
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6331716/ https://ncbi.nlm.nih.gov/pubmed/30504269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899384 |
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