Miro proteins prime mitochondria for Parkin translocation and mitophagy

The Parkinson's disease‐associated protein kinase PINK1 and ubiquitin ligase Parkin coordinate the ubiquitination of mitochondrial proteins, which marks mitochondria for degradation. Miro1, an atypical GTPase involved in mitochondrial trafficking, is one of the substrates tagged by Parkin after...

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Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: Safiulina, Dzhamilja, Kuum, Malle, Choubey, Vinay, Gogichaishvili, Nana, Liiv, Joanna, Hickey, Miriam A, Cagalinec, Michal, Mandel, Merle, Zeb, Akbar, Liiv, Mailis, Kaasik, Allen
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331716/
https://ncbi.nlm.nih.gov/pubmed/30504269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899384
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