BECN1 is involved in the initiation of mitophagy: It facilitates PARK2 translocation to mitochondria

The autophagy protein BECN1/Beclin 1 is known to play a central role in autophagosome formation and maturation. The results presented here demonstrate that BECN1 interacts with the Parkinson disease-related protein PARK2. This interaction does not require PARK2 translocation to mitochondria and occu...

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Autors principals: Choubey, Vinay, Cagalinec, Michal, Liiv, Joanna, Safiulina, Dzhamilja, Hickey, Miriam A, Kuum, Malle, Liiv, Mailis, Anwar, Tahira, Eskelinen, Eeva-Liisa, Kaasik, Allen
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2014
Matèries:
Basic Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091171/
https://ncbi.nlm.nih.gov/pubmed/24879156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.28615
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