Spatial Parkin Translocation and Degradation of Damaged Mitochondria Via Mitophagy in Live Cortical Neurons

Mitochondria are essential for neuronal survival and function. Proper degradation of aged and damaged mitochondria through mitophagy is a key cellular pathway for mitochondrial quality control. Recent studies have indicated that PINK1/Parkin-mediated pathways ensure mitochondrial integrity and funct...

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Bibliographic Details
Main Authors: Cai, Qian, Zakaria, Hesham Mostafa, Simone, Anthony, Sheng, Zu-Hang
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313683/
https://ncbi.nlm.nih.gov/pubmed/22342752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.02.005
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