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Long time-lapse imaging reveals unique features of PARK2/Parkin-mediated mitophagy in mature cortical neurons

Proper degradation of aged and damaged mitochondria through mitophagy is essential to ensure mitochondrial integrity and function. Translocation of PARK2/Parkin onto damaged mitochondria induces mitophagy in many non-neuronal cell types. However, direct evidence showing PARK2-mediated mitophagy in m...

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Détails bibliographiques
Auteurs principaux: Cai, Qian, Zakaria, Hesham Mostafa, Sheng, Zu-Hang
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427264/
https://ncbi.nlm.nih.gov/pubmed/22739253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.20218
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