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Long time-lapse imaging reveals unique features of PARK2/Parkin-mediated mitophagy in mature cortical neurons
Proper degradation of aged and damaged mitochondria through mitophagy is essential to ensure mitochondrial integrity and function. Translocation of PARK2/Parkin onto damaged mitochondria induces mitophagy in many non-neuronal cell types. However, direct evidence showing PARK2-mediated mitophagy in m...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3427264/ https://ncbi.nlm.nih.gov/pubmed/22739253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.20218 |
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