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USP8 and PARK2/parkin-mediated mitophagy
The Parkinson disease (PD)-associated E3-ubiquitin (Ub) ligase PARK2/parkin plays a central role in many stress response pathways, and in particular, in mitochondrial quality control. Within this pathway, PARK2 activation is accompanied by a robust increase in its autoubiquitination, followed by cle...
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| Pubblicato in: | Autophagy |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4502724/ https://ncbi.nlm.nih.gov/pubmed/25700639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1009794 |
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