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USP8 and PARK2/parkin-mediated mitophagy

The Parkinson disease (PD)-associated E3-ubiquitin (Ub) ligase PARK2/parkin plays a central role in many stress response pathways, and in particular, in mitochondrial quality control. Within this pathway, PARK2 activation is accompanied by a robust increase in its autoubiquitination, followed by cle...

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書目詳細資料
發表在:Autophagy
Main Authors: Durcan, Thomas M, Fon, Edward A
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2015
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502724/
https://ncbi.nlm.nih.gov/pubmed/25700639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1009794
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