Temporal dynamics of PARK2/parkin and OPTN/optineurin recruitment during the mitophagy of damaged mitochondria

Damaged mitochondria are selectively degraded via autophagy in a regulated pathway known as mitophagy. Parkinson disease-linked proteins PINK1 (PTEN induced putative kinase 1) and PARK2 (parkin RBR E3 ubiquitin protein ligase) are recruited to the outer mitochondrial membrane upon mitochondrial dama...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Autophagy
Egile Nagusiak: Wong, Yvette C, Holzbaur, Erika L F
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2015
Gaiak:
Autophagic Puncta
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502688/
https://ncbi.nlm.nih.gov/pubmed/25801386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1009792
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