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SCY-078, a Novel Fungicidal Agent, Demonstrates Distribution to Tissues Associated with Fungal Infections during Mass Balance Studies with Intravenous and Oral [(14)C]SCY-078 in Albino and Pigmented Rats
SCY-078, a fungicidal β-1,3-glucan synthesis inhibitor administered as intravenous or oral [(14)C]SCY-078 to rats, was distributed primarily into tissues associated with invasive fungal disease (kidney, lung, liver, spleen, bone marrow, muscle, vaginal tissue, and skin) to levels exceeding those in...
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6355592/ https://ncbi.nlm.nih.gov/pubmed/30478166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02119-18 |
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