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Chemoselective α,β‐Dehydrogenation of Saturated Amides

We report a method for the selective α,β‐dehydrogenation of amides in the presence of other carbonyl moieties under mild conditions. Our strategy relies on electrophilic activation coupled to in situ selective selenium‐mediated dehydrogenation. The α,β‐unsaturated products were obtained in moderate...

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Publicado en:Angew Chem Int Ed Engl
Main Authors: Teskey, Christopher J., Adler, Pauline, Gonçalves, Carlos R., Maulide, Nuno
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348382/
https://ncbi.nlm.nih.gov/pubmed/30332524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201808794
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