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Chemoselective Intermolecular Cross-Enolate-Type Coupling of Amides

[Image: see text] A new approach for the synthesis of 1,4-dicarbonyl compounds is reported. Chemoselective activation of amide carbonyl functionality and subsequent umpolung viaN-oxide addition generates an electrophilic enolonium species that can be coupled with a wide range of nucleophilic enolate...

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書目詳細資料
發表在:J Am Chem Soc
Main Authors: Kaiser, Daniel, Teskey, Christopher J., Adler, Pauline, Maulide, Nuno
格式: Artigo
語言:Inglês
出版: American Chemical Society 2017
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691317/
https://ncbi.nlm.nih.gov/pubmed/29099184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b08813
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