A carregar...

Chemoselective Alpha‐Deuteration of Amides via Retro‐ene Reaction

A synthetically convenient approach for the direct α‐deuteration of amides is reported. This mechanistically unusual process relies on a retro‐ene‐type process, triggered by the addition of deuterated dimethyl sulfoxide to a keteniminium intermediate, generated through electrophilic amide activation...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Porte, Vincent, Di Mauro, Giovanni, Schupp, Manuel, Kaiser, Daniel, Maulide, Nuno
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756638/
https://ncbi.nlm.nih.gov/pubmed/33035360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202004103
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!