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Unified Approach to the Chemoselective α-Functionalization of Amides with Heteroatom Nucleophiles
[Image: see text] Functionalization at the α-position of carbonyl compounds has classically relied on enolate chemistry. As a result, the generation of a new C–X bond, where X is more electronegative than carbon requires an oxidation event. Herein we show that, by rendering the α-position of amides...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Am Chem Soc |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Chemical
Society
2019
|
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6879173/ https://ncbi.nlm.nih.gov/pubmed/31714077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b06956 |
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