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Chemoselective formal β-functionalization of substituted aliphatic amides enabled by a facile stereoselective oxidation event
Aliphatic C–H functionalization is a topic of current intense interest in organic synthesis. Herein, we report that a facile and stereoselective dehydrogenation event enables the functionalization of aliphatic amides at different positions in a one-pot fashion. Derivatives of relevant pharmaceutical...
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| Publicado en: | Chem Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Royal Society of Chemistry
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6977552/ https://ncbi.nlm.nih.gov/pubmed/32015806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc03715b |
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