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Enhanced phosphorylation of T153 in soluble tau is a defining biochemical feature of the A152T tau risk variant
Pathogenic mutations in the tau gene (microtubule associated protein tau, MAPT) are linked to the onset of tauopathy, but the A152T variant is unique in acting as a risk factor for a range of disorders including Alzheimer’s disease (AD), progressive supranuclear palsy (PSP), corticobasal degeneratio...
में बचाया:
| में प्रकाशित: | Acta Neuropathol Commun |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
BioMed Central
2019
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6345061/ https://ncbi.nlm.nih.gov/pubmed/30674342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0661-2 |
| टैग : |
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