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PERK Signaling Regulates Extracellular Proteostasis of an Amyloidogenic Protein During Endoplasmic Reticulum Stress

The PERK arm of the unfolded protein response (UPR) regulates cellular proteostasis and survival in response to endoplasmic reticulum (ER) stress. However, the impact of PERK signaling on extracellular proteostasis is poorly understood. We define how PERK signaling influences extracellular proteosta...

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Publicado en:Sci Rep
Main Authors: Romine, Isabelle C., Wiseman, R. Luke
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344643/
https://ncbi.nlm.nih.gov/pubmed/30675021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37207-0
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