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PERK Signaling Regulates Extracellular Proteostasis of an Amyloidogenic Protein During Endoplasmic Reticulum Stress

The PERK arm of the unfolded protein response (UPR) regulates cellular proteostasis and survival in response to endoplasmic reticulum (ER) stress. However, the impact of PERK signaling on extracellular proteostasis is poorly understood. We define how PERK signaling influences extracellular proteosta...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Romine, Isabelle C., Wiseman, R. Luke
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344643/
https://ncbi.nlm.nih.gov/pubmed/30675021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37207-0
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