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PERK Signaling Regulates Extracellular Proteostasis of an Amyloidogenic Protein During Endoplasmic Reticulum Stress

The PERK arm of the unfolded protein response (UPR) regulates cellular proteostasis and survival in response to endoplasmic reticulum (ER) stress. However, the impact of PERK signaling on extracellular proteostasis is poorly understood. We define how PERK signaling influences extracellular proteosta...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Romine, Isabelle C., Wiseman, R. Luke
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344643/
https://ncbi.nlm.nih.gov/pubmed/30675021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37207-0
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