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PERK Signaling Regulates Extracellular Proteostasis of an Amyloidogenic Protein During Endoplasmic Reticulum Stress

The PERK arm of the unfolded protein response (UPR) regulates cellular proteostasis and survival in response to endoplasmic reticulum (ER) stress. However, the impact of PERK signaling on extracellular proteostasis is poorly understood. We define how PERK signaling influences extracellular proteosta...

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Publicat a:Sci Rep
Autors principals: Romine, Isabelle C., Wiseman, R. Luke
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344643/
https://ncbi.nlm.nih.gov/pubmed/30675021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37207-0
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