The PERK Arm of the Unfolded Protein Response Regulates Mitochondrial Morphology during Acute Endoplasmic Reticulum Stress

Endoplasmic reticulum (ER) stress is transmitted to mitochondria and is associated with pathologic mitochondrial dysfunction in diverse diseases. The PERK arm of the unfolded protein response (UPR) protects mitochondria during ER stress through the transcriptional and translational remodeling of mit...

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Vydáno v:Cell Rep
Hlavní autoři: Lebeau, Justine, Saunders, Jaclyn M., Moraes, Vivian W.R., Madhavan, Aparajita, Madrazo, Nicole, Anthony, Mary C., Wiseman, R. Luke
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870888/
https://ncbi.nlm.nih.gov/pubmed/29539413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.02.055
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