ロード中...

Loss of two Akt isoforms in hematopoietic cells diminished monocyte and macrophage survival and reduces atherosclerosis in Ldl-receptor null mice

OBJECTIVE: Macrophages express three Akt isoforms, Akt1, Akt2 and Akt3, which display isoform-specific functions but may be redundant in terms of Akt survival signaling. We hypothesize that loss of two Akt isoforms in macrophages will suppress their ability to survive and modulate the development of...

詳細記述

保存先:
書誌詳細
出版年:Arterioscler Thromb Vasc Biol
主要な著者: Babaev, Vladimir R., Ding, Lei, Zhang, Youmin, May, James M., Ramsey, Stephen A., Vickers, Kasey C., Linton, MacRae F.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344270/
https://ncbi.nlm.nih.gov/pubmed/30567482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.312206
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!