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Macrophage deficiency of Akt2 reduces atherosclerosis in Ldlr null mice
Macrophages play crucial roles in the formation of atherosclerotic lesions. Akt, a serine/threonine protein kinase B, is vital for cell proliferation, migration, and survival. Macrophages express three Akt isoforms, Akt1, Akt2, and Akt3, but the roles of Akt1 and Akt2 in atherosclerosis in vivo rema...
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| 出版年: | J Lipid Res |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Biochemistry and Molecular Biology
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4617132/ https://ncbi.nlm.nih.gov/pubmed/25240046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M050633 |
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