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Accurate Prediction of Amide Exchange in the Fast Limit Reveals Thrombin Allostery
Amide hydrogen/deuterium exchange mass spectrometry (HDXMS) of proteins has become extremely popular for identifying ligand-binding sites, protein-protein interactions, intrinsic disorder, and allosteric changes upon protein modification. Such phenomena are revealed when amide exchange is measured i...
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| Publié dans: | Biophys J |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Biophysical Society
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6342732/ https://ncbi.nlm.nih.gov/pubmed/30558884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.11.023 |
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