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Amide H/(2)H Exchange Reveals a Mechanism of Thrombin Activation
Thrombin is a dual action serine protease in the blood clotting cascade. Similar to other clotting factors, thrombin is mainly present in the blood in a zymogen form, prothrombin. Although the two cleavage events required to activate thrombin are well known, little is known about why the thrombin pr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2535819/ https://ncbi.nlm.nih.gov/pubmed/16784223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060405h |
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