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Understanding and overcoming trade-offs between antibody affinity, specificity, stability and solubility
The widespread use of monoclonal antibodies for therapeutic applications has led to intense interest in optimizing several of their natural properties (affinity, specificity, stability, solubility and effector functions) as well as introducing non-natural activities (bispecificity and cytotoxicity m...
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| 出版年: | Biochem Eng J |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6338232/ https://ncbi.nlm.nih.gov/pubmed/30666176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bej.2018.06.003 |
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