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Characterization of CD38 in the major cell types of the heart: endothelial cells highly express CD38 with activation by hypoxia-reoxygenation triggering NAD(P)H depletion

The NAD(P)(+)-hydrolyzing enzyme CD38 is activated in the heart during the process of ischemia and reperfusion, triggering NAD(P)(H) depletion. However, the presence and role of CD38 in the major cell types of the heart are unknown. Therefore, we characterize the presence and function of CD38 in car...

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Detalles Bibliográficos
Publicado en:Am J Physiol Cell Physiol
Main Authors: Boslett, James, Hemann, Craig, Christofi, Fedias L., Zweier, Jay L.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335017/
https://ncbi.nlm.nih.gov/pubmed/29187364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00139.2017
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