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Characterization of CD38 in the major cell types of the heart: endothelial cells highly express CD38 with activation by hypoxia-reoxygenation triggering NAD(P)H depletion

The NAD(P)(+)-hydrolyzing enzyme CD38 is activated in the heart during the process of ischemia and reperfusion, triggering NAD(P)(H) depletion. However, the presence and role of CD38 in the major cell types of the heart are unknown. Therefore, we characterize the presence and function of CD38 in car...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Boslett, James, Hemann, Craig, Christofi, Fedias L., Zweier, Jay L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335017/
https://ncbi.nlm.nih.gov/pubmed/29187364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00139.2017
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