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Inhibition of CD38 with the Thiazoloquin(az)olin(on)e 78c Protects the Heart against Postischemic Injury
Inhibition of and genetic deletion of the NAD(P)(+) hydrolase [NAD(P)ase] CD38 have been shown to protect against ischemia/reperfusion (I/R) injury in rat and mouse hearts. CD38 has been shown to enhance salvage of NADP(H), which in turn prevents impairment of endothelial nitric oxide synthase funct...
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| Udgivet i: | J Pharmacol Exp Ther |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Pharmacology and Experimental Therapeutics
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6413770/ https://ncbi.nlm.nih.gov/pubmed/30635470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.254557 |
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