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Homologous recombination-mediated targeted integration in monkey embryos using TALE nucleases

BACKGROUND: Non-human primate (NHP) models can closely mimic human physiological functions and are therefore highly valuable in biomedical research. Genome editing is now developing rapidly due to the precision and efficiency offered by engineered site-specific endonuclease-based systems, such as tr...

詳細記述

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書誌詳細
出版年:BMC Biotechnol
主要な著者: Chu, Chu, Yang, Zhaohui, Yang, Jiayin, Yan, Li, Si, Chenyang, Kang, Yu, Chen, Zhenzhen, Chen, Yongchang, Ji, Weizhi, Niu, Yuyu
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6334428/
https://ncbi.nlm.nih.gov/pubmed/30646876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-018-0494-2
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