Homologous recombination-mediated targeted integration in monkey embryos using TALE nucleases

BACKGROUND: Non-human primate (NHP) models can closely mimic human physiological functions and are therefore highly valuable in biomedical research. Genome editing is now developing rapidly due to the precision and efficiency offered by engineered site-specific endonuclease-based systems, such as tr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:BMC Biotechnol
Hauptverfasser: Chu, Chu, Yang, Zhaohui, Yang, Jiayin, Yan, Li, Si, Chenyang, Kang, Yu, Chen, Zhenzhen, Chen, Yongchang, Ji, Weizhi, Niu, Yuyu
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6334428/
https://ncbi.nlm.nih.gov/pubmed/30646876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-018-0494-2
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge