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Homologous recombination-mediated targeted integration in monkey embryos using TALE nucleases
BACKGROUND: Non-human primate (NHP) models can closely mimic human physiological functions and are therefore highly valuable in biomedical research. Genome editing is now developing rapidly due to the precision and efficiency offered by engineered site-specific endonuclease-based systems, such as tr...
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| Pubblicato in: | BMC Biotechnol |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6334428/ https://ncbi.nlm.nih.gov/pubmed/30646876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-018-0494-2 |
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