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Efficient homologous recombination-mediated genome engineering in zebrafish using TALE nucleases
Custom-designed nucleases afford a powerful reverse genetic tool for direct gene disruption and genome modification in vivo. Among various applications of the nucleases, homologous recombination (HR)-mediated genome editing is particularly useful for inserting heterologous DNA fragments, such as GFP...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Company of Biologists
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4197590/ https://ncbi.nlm.nih.gov/pubmed/25249466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.108019 |
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