Homologous recombination-mediated targeted integration in monkey embryos using TALE nucleases

BACKGROUND: Non-human primate (NHP) models can closely mimic human physiological functions and are therefore highly valuable in biomedical research. Genome editing is now developing rapidly due to the precision and efficiency offered by engineered site-specific endonuclease-based systems, such as tr...

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Detalhes bibliográficos
Publicado no:BMC Biotechnol
Main Authors: Chu, Chu, Yang, Zhaohui, Yang, Jiayin, Yan, Li, Si, Chenyang, Kang, Yu, Chen, Zhenzhen, Chen, Yongchang, Ji, Weizhi, Niu, Yuyu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6334428/
https://ncbi.nlm.nih.gov/pubmed/30646876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-018-0494-2
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