Homologous recombination-mediated targeted integration in monkey embryos using TALE nucleases

BACKGROUND: Non-human primate (NHP) models can closely mimic human physiological functions and are therefore highly valuable in biomedical research. Genome editing is now developing rapidly due to the precision and efficiency offered by engineered site-specific endonuclease-based systems, such as tr...

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Bibliografiske detaljer
Udgivet i:BMC Biotechnol
Main Authors: Chu, Chu, Yang, Zhaohui, Yang, Jiayin, Yan, Li, Si, Chenyang, Kang, Yu, Chen, Zhenzhen, Chen, Yongchang, Ji, Weizhi, Niu, Yuyu
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6334428/
https://ncbi.nlm.nih.gov/pubmed/30646876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-018-0494-2
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