DNMT3L facilitates DNA methylation partly by maintaining DNMT3A stability in mouse embryonic stem cells

DNMT3L (DNMT3-like), a member of the DNMT3 family, has no DNA methyltransferase activity but regulates de novo DNA methylation. While biochemical studies show that DNMT3L is capable of interacting with both DNMT3A and DNMT3B and stimulating their enzymatic activities, genetic evidence suggests that...

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書目詳細資料
發表在:Nucleic Acids Res
Main Authors: Veland, Nicolas, Lu, Yue, Hardikar, Swanand, Gaddis, Sally, Zeng, Yang, Liu, Bigang, Estecio, Marcos R, Takata, Yoko, Lin, Kevin, Tomida, Mary W, Shen, Jianjun, Saha, Debapriya, Gowher, Humaira, Zhao, Hongbo, Chen, Taiping
格式: Artigo
語言:Inglês
出版: Oxford University Press 2019
主題:
Gene regulation, Chromatin and Epigenetics
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326784/
https://ncbi.nlm.nih.gov/pubmed/30321403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky947
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