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DNMT3L facilitates DNA methylation partly by maintaining DNMT3A stability in mouse embryonic stem cells
DNMT3L (DNMT3-like), a member of the DNMT3 family, has no DNA methyltransferase activity but regulates de novo DNA methylation. While biochemical studies show that DNMT3L is capable of interacting with both DNMT3A and DNMT3B and stimulating their enzymatic activities, genetic evidence suggests that...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6326784/ https://ncbi.nlm.nih.gov/pubmed/30321403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky947 |
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